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How does stability analysis complement zeta potential measurement and laser diffraction particle size analysis?

2024-09-24WIKI

Zeta potential and laser diffraction particle size analysis can be applied to indicate the stability of a dispersion. Dispersion with a large absolute value of zeta potential or small particle size is considered stable from general experiences. However, it is risky to evaluate stability with only one parameter. Stability analysis based on SMLS is a comprehensive solution, which considers all factors that can affect stability. The combination of stability analysis and zeta potential measurement or laser diffraction particle size analysis reveals the relationship between the stability of dispersion and its zeta potential or particle size, which facilitates formulation development and quality control.

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