Research on Particle Size Measurement of Lactose by Laser Particle Size Analyzer
21 Jul 2021
Lactose is one of the most common kinds of tablet excipients. The USP has clear regulations on raw materials particle sizing by laser diffraction method, such as the structure and principle of the instrument, the specific method of dry and wet dispersions, the factors in the measurement process, etc. However, for specific lactose, there is no related instruction on how to choose the dispersive pressure and how to evaluate the results of dry and wet methods. This note carried out a systematic research on lactose particle size distribution measurement in accordance with the USP and the ISO 13320.
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