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생물학

Introduction

베터사이즈에서 제공하는 분석 기기는 생물학 및 생명 과학 연구에서 중요한 폴리머 특성인 입자 크기, 제타 전위, 분자량을 정확하고 신뢰성 있게 측정할 수 있는 고급 분석 장비입니다. 이러한 특성들은 단백질 및 고분자와 같은 폴리머의 안정성과 효능을 결정하는 데 중요한 요소입니다.

 

생명 과학 연구 분야에서 폴리머는 단백질, 폴리펩타이드, 항원, 고분자 등을 포함한 주요 연구 대상입니다. 대부분의 폴리머는 작은 구성 단위로 이루어져 있습니다. 예를 들어, 단백질은 아미노산이라는 구성 단위로 이루어져 있으며, 아미노산 사슬은 펩타이드 결합을 통해 3차원 구조로 접히고 결합됩니다. 이들 단백질의 구조, 표면 전하 및 아미노산의 조합은 단백질의 특성뿐만 아니라 궁극적으로 효능과 안정성에 영향을 미칩니다. 대부분의 폴리머는 수용액에서 합성되고 사용되므로, 폴리머 현탁액의 특성을 연구하는 것이 생물학적 연구에서 중요한 도전 과제가 됩니다.

 

단백질 현탁액의 핵심 지표는 제타 전위로, 이는 단백질 응집 가능성을 나타냅니다. 제타 전위 외에도, 입자 크기와 분자량은 연구 중에 주목할 만한 중요한 특성입니다. 예를 들어, 온도에 민감한 일부 단백질은 환경 온도가 상승할 때 변성되며, 이때 단백질의 분자량과 입자 크기를 면밀히 모니터링하는 것이 열적 안정성 분석에 유용합니다.

 

베터사이즈의 BeNano 시리즈는 액체 현탁액 시스템에서 폴리머의 제타 전위, 입자 크기, 분자량을 정밀하게 측정할 수 있는 혁신적인 기술을 제공하여 생물학 및 생명 과학 연구의 연구 개발 속도를 가속화합니다.

Citations

  • Bettersizer 2600

    Functional redundancy as an indicator for evaluating functional diversity of macrobenthos under the mussel raft farm near Gouqi Island

    DOI: 10.1016/j.aquaculture.2023.740024 Read Article Go logo
    Zhejiang Ocean University | 2024
    Biological traits analysis (BTA) helps to evaluate the effects of different environmental variables on the traits-based functional composition of macrobenthos. However, research on functional traits of macrobenthos under mussel farming is limited. We investigated the spatial and temporal response of the benthic system in terms of taxonomic and functional diversity to environmental variables of farming and natural stressors resulting from suspended mussel farming near Gouqi Island of eastern China Sea. The functional traits of macrobenthic assemblages under mussel farming were characterized by “medium adult body size”, “vermiform body form”, “high flexibility”, “infauna”, “semi-motile”, “gonochoristic”, “surface deposit-feeders”, “carnivores”, “semi-motile burrowers”, and “tube-dwellers”. Functional redundancy was stable in response to mussel farming stresses among seasons, whereas species diversity showed efficient to evaluate natural variables. Functional diversity was significantly affected by farming stressors rather than natural variables, Further analysis using multivariate methods together with continuous monitoring were highlighted to evaluate the impacts of mussel farming. Our results reinforce the importance of macrobenthic species and functional traits analysis to evaluate human stresses driven impacts in offshore ecosystems. By analysing the environmental variables with different sources, independently, we concluded the main effects of human pressures on macrobenthic community. Such distinction could be particularly effective to isolate variable environmental descriptors and evaluate their effects on functional diversity, making the current approach promising for the evaluation of ecological effects of anthropogenic stressors in aquaculture areas.
  • Bettersizer 2600

    Degradation characteristics and utilization strategies of a covalent bonded resin-based solid amine during capturing CO2 from flue gas

    DOI: 10.1016/j.seppur.2023.125621 Read Article Go logo
    China University of Petroleum | 2024

    In this study, various types of degradation as well as attrition which are possibly encountered in a circulating fluidized bed temperature swing adsorption (CFB-TSA) process, were conducted experimentally to evaluate the stability of a resin-based solid amine sorbent. Other characterizations methods, such as elemental analysis (EA), Fourier transform infrared spectroscopy (FTIR) etc. were applied to further reveal the degradation mechanisms. The results showed that thermal degradation occurs from 140–160 °C due to the decomposition of amine group. The CO2-induced degradation occurs from a higher temperature of 160–180 °C accompanied by the production of urea. Hydrothermal stability is good below 130 °C, but the ionic impurities in steam crystalized on particle surface can accelerate the degradation. Oxidative degradation is the most harmful, which starts at a lower temperature of 70–80 °C with the formation of aldehyde. The existence of H2O in atmosphere can alleviate the oxidative and CO2-induced degradations. The employed sorbent has a very low attrition index of 0.05, which is 1–2 orders lower than typical commercial fluidized bed catalysts. Based on the results of stability evaluation, some design suggestions for proper utilization of this sorbent or other similar resin-based sorbents have been provided in an industrial CFB-TSA process.

  • Bettersizer 2600

    De-branching of starch molecules enhanced the complexation with chitosan and its potential utilization for delivering hydrophobic compounds

    DOI: 10.1016/j.foodhyd.2023.109498 Read Article Go logo
    Shihezi University | 2024
    The current study aimed to prepare the complexes between debranched-waxy corn starch and chitosan polymers (DBS-CS), and then investigated their corresponding structural characteristics, rheological property and potent application in Pickering emulsion. The results indicated that the existence of chitosan significantly inhibited starch short-range molecular rearrangement for all DBS-CS samples, which was manipulated by both debranching treatment and chitosan content. Interestingly, this is the first study to reveal that the outstanding peak at 1.8 ppm in 1H NMR spectrum for sample DBS-CS was gradually shifted towards a lower-field region following an increased chitosan content. Moreover, the debranching treatment shifted the crystallinity pattern from A-type to B-type and the relative crystallinity of DBS-CS decreased gradually with the increased content of CS. All samples had a pseudoplastic fluid and shear-thinning behavior with an enhanced shear resistance following the complexation. The DBS-CS was applied in a Pickering emulsion for showing a greater emulsifying stability and a lower gel strength than native NS-CS prepared emulsion. Importantly, the encapsulation ability of curcumin in the DBS-CS emulsion was significantly improved, followed by an increase of 15.45% for its corresponding bioavailability compared to the control. Therefore, this study might highlight a potential carrier for delivering the bioactive substances in a green pattern.
  • Bettersizer 2600

    Heat-induced aggregation behavior of wheat gluten after adding citrus pectin with different esterification degree

    DOI: 10.1016/j.foodhyd.2023.109420 Read Article Go logo
    Gansu Agricultural University | 2024
    Wheat gluten aggregation during heat treatment is beneficial to the final quality of gluten-based products. Exogenous pectin can affect gluten aggregation. However, the effect of pectin with different degrees of esterification on the heat-induced aggregation behavior of gluten and its possible mechanism are still unclear. Thus, the heat-induced aggregation behavior of gluten after adding pectin with different esterification degree was studied in this study. When the temperature was raised from 25 °C to 95 °C, pectin affected gluten aggregation and was related to the degree of esterification. Specifically, the results of rheological properties and particle size indicated that low-ester pectin improved the viscoelasticity of gluten and promoted gluten aggregation. Thermal properties revealed that enthalpy of gluten added with low-ester pectin (37%) increased from 92.96 J/g to 95.40 J/g during heating process. Structurally, the fluorescence intensity and surface hydrophobicity of gluten added with low-ester pectin (37%) were lower than those added with high-ester pectin (73%). In addition, low-ester pectin (37%) significantly increased the disulfide bond content (from 15.31 μmol/g to 18.06 μmol/g) and maintained β-sheet content of gluten compared with gluten alone at 95 °C, indicating that low-ester pectin was more likely to induce gluten aggregation. However, scanning electron microscope showed that the gluten added with low-ester pectin (46%) exhibited a denser network structure at 95 °C than that added with low-ester pectin (37%). These results will provide a theoretical base for the regulation of gluten aggregation and the quality of gluten-based products by pectin with different esterification degree.
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